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Abstract : Prostate cancer (Pca) is one of the most common tumors in men. In many risk factors causing Pca, several interpretations have revealed that certain specific gene variants and viral infections are strong candidates for the initiation of prostate tumors. Indeed, cancerous tissue infections of the prostate have been reported by the presence of several types of viruses among these viruses there are human papillomaviruses (HPV). The general objective of the present study of this article is to carry out the genotyping of the oncogenic HPV virus of types 18,11,6,45,58,35 and 53 in 10 blood samples already positive for HPV in patients with Pca in the Moroccan population. HPV Deoxyribonucleic Acid (DNA)detection and genotyping were performed by nested- Polymerase Chain Reaction (PCR). To achieve our objectives, 10 blood samples are already positive for HPV in patients with Pca. The viral DNA was extracted and calibrated and the target genes were amplified by PCR using specific primers in 2% agarose gel and visualization under UV. The most common genotypes detected among the patients were HPV 18 (30%), HPV 35 (20%), HPV 45 (20%), HPV 58 (10%), HPV 6(10%), HPV 11(10%), and HPV 53 (0%). HPV infection was common in the study population. The most common genotypes were HPV 6, 11,58,18, and 53, This discovery advances our understanding of HPV epidemiology research and has implications for future research targeted at identifying populations at risk for Pca.

Abstract : Community service (PKM) entitled: Community Empowerment of the Sido Maju II Farmer Group in Wonoharjo Village, Kemusu District, Boyolali Regency, through the Cultivation of Garut Plants (Marantha arundinaceae l.), processing of chips, and arrowroot flour carried out as a continuation of the results of the author's preliminary community service in 2020 where the Garut plant has the potential to be developed in the Wonorejo area, the use of manure provides real production results. Likewise, balanced fertilization in the form of manure and NPK gives good results for arrowroot. arrowroot is a source of potential food _ for part of society, with having index glycemic low and content carbohydrate high. Flour arrowroot could replace wheat as an ingredient in food and industry. Arrowroot chips can be obtained from the basic ingredients of arrowroot, the great public interest in arrowroot products in the form of chips and arrowroot flour because the more they understand the benefits of processed arrowroot products, the demand for arrowroot to be processed and marketed is increasing so that it is necessary to empower Garut farmers. Community empowerment of the Sido Maju I, II Farmers Group, arrowroot production is relatively high, reaching 4 tons/ha, but post-harvest management and arrowroot-based product diversification are still low. In order to support the needs of the post-harvest process and business diversification of the SidoMaju II farmer group, it is necessary to provide training solutions and apply the technology that has been developed: Cultivation of Garut Plants for maximum production, making chips and arrowroot flour, given the demand for processed arrowroot in the Boyolali region, Surakarta is prospective, so giving A grated arrowroot tool with a capacity of 20 kg of arrowroot flour has been provided to the Sido Maju Farmers Group to speed up the production process, as well as arrowroot tuber flaking tools for the production of arrowroot chips, so that training in post-harvest management in the form of arrowroot-based food processing, namely chips and arrowroot flour can be empowered in the Sido Maju Wonoharjo farmer group environment, Kemusu Boyolali, Empowerment through arrowroot processing can increase community income, especially Members of the Maju Farmer Group by 30%, citizen participation has increased by 20%.

Abstract : The First Thousand Days of Life (HPK) is a period of 270 days (9 months) in the womb and 730 days (the first 2 years) post-birth. A thousand HPK is very important because the impact of malnutrition in this period is permanent and long-term. The effect of malnutrition in the womb can extend to three generations. Evidence from India that malnourished children are likely to become short adults and then tend to give birth to small babies who are at risk of low risk of dwelling achievement and ultimately have low economic status. Stunting at an early age can predict cognitive performance and the risk of coroner's heart disease in adults (Achadi EL, 2013). The purpose of this study is to find out the risk factors for pregnant women related to stunting in babies in Bungursari District, Tasikmalaya City. Benefits: The benefits of research are to provide input to policyholders and the public that the risk factors experienced by hami mothers will cause stunting events in the baby she is about to give birth to. This research methodology uses kinds prospective cohort research, using quantitative analysis. The subjects of the study were neonatal babies and their mothers. The study was conducted in Bungursari Subdistrict, Tasikmalaya City from May to December 2017 with the sampling technique being proportionate stratified random sampling. The conclusion of the study results is that there is no relationship between socioeconomic characteristics, energy intake, iron intake, zinc intake, and nutritional status of pregnant women with stunting events in infants. There is a meaningful relationship between the history of infectious diseases of pregnant women (p = 0.41) and the incidence of stunting in infants.

Abstract : Bioactive materials have been used in every field of dentistry and medicine. These materials are broadly used in the field of conservative dentistry for regeneration, repair and reconstruction. These materials are available in different form and composition that acts directly on vital tissue inducing its healing and repair. These materials directly function because of induction of various growth factors and different cells. Thus, this article describes various bioactive materials, the form in which they are available and its uses. As a conclusion the rapidly emerging domain of bioactivity is an area of great focus as it is intriguing and exciting topic in dental field. Bioactive restorative materials continue to show interesting potential offer significant benefits for both dentist and patient. Their applications in dentistry include remineralization of hard tissues, maintenance of long-duration dental bonded restorations and healing of bony defects.

Abstract : COVID-19 is a worldwide epidemic with high fatality. Several COVID vaccines have been created, the first of which were produced by Sinopharm and Pfizer. To compare interferon-gamma levels before and after vaccination for each of the two vaccines Pfizer and Sinopharm. This a cross sectional study in which 119 patients were assessed; 53 patients were vaccinated with Pfizer/BioNTech, 18 with Sinopharm, and 48 unvaccinated subjects. After 3 months of the 1st vaccine dose, the mean level of IFN-γ in vaccinated and unvaccinated subjects were 42.49 ± 26.00, 34.53 ± 21.41 respectively, while after 3 months of the 2nd dose, the mean level of IFN-γ in vaccinated and unvaccinated subjects were 38.09 ± 26.50, 28.13 ± 17.30 respectively. No significant difference in interferon-gamma levels was detected between Sinopharm and Pfizer groups. The Vaccinated groups showed a significant increase in the levels of IFN- γ after the second dose of vaccines and both vaccines showed the same efficacy as there is no significant difference in interferon-gamma levels was detected between both groups.