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Abstract : Globally, the prevalence of anemia was highest among children under five years, at 39.7%. The main factor is iron deficiency (ID). However, the particular iron status parameter for early detection of ID in babies has yet to be determined. To establish reference intervals for reticulocyte hemoglobin equivalent (Ret-He) in healthy term babies seven days after birth. A cross-sectional study of Ret-He in healthy-term babies seven days after delivery was conducted from April to December 2018 at Idaman Banjarbaru Hospital. Two hundred seventy-seven healthy-term babies met the inclusion criteria. There were 145 (52.35%) male babies and 132 (47.65%) female babies. The reference interval for Ret-He at P2.5-P97.5, P3-P97, and mean ±2SD was 29.06 to 40.11pg, 29.24 to 39.97 pg, 29,46 to 38.01 pg, respectively. In addition, the reference interval for male babies Ret-He at P2.5-P97.5, P3-P97, and mean ±2SD was 28.17 to 41.44 pg, 28.54 to 41.25 pg, and 29.28 to 41.24 pg, respectively. The reference interval for female babies Ret-He at P2.5-P97.5, P3-P97, and mean ±2SD was 29.73 to 39.80, 30.00 to 39.60, 29.71 to 0.43 pg, respectively. Conclusion: The reference interval for Ret-He in healthy-term babies one week after birth can be used as a benchmark.

Abstract : SARS-COV2 causes highly contagious, brand-new emerging disease called Covid-19. Unlike other zoonotic disease, the disease transmit human to human. As massive mobility spread throughout the world, we should find a method to detect and stop the transmission. Hospital-based surveillance was one of surveillance strategy that was effective to early detection and easy to apply. This study described application of hospital-based surveillance strategy in one of national referral hospital for infectious disease. We analyse trends in People Under Observation (PUO), Patients Under Investigation (PUI), and mortality rate in beginning of pandemic era in Indonesia. These findings have become part of the National guideline for Covid-19 prevention and control in the surveillance and clinical management chapter. We studied PUO in early pandemic era in Indonesia from February 1st to May 31st 2020. We also analyse inpatient cases (PUI) of COVID-19 in Sulianti Saroso Infectious Disease Hospital throughout the year. We analysed hospital-based surveillance system, by the case terminology proposed in the National Guideline. Case confirmed was signed by positive RT-PCR via nasopharynx and oropharynx swab. Data analysis was done by performing frequency measurement and chi-square. We screened a total of 2555 PUO during the study in the beginning of pandemic in Indonesia with travel history to region where covid-19 had already presented, history of close contact and/or presented covid-19 like symptoms. Until the end of 2022, we treated 3928 Patients Under Investigation which 3694 of them (82.6%) were confirmed COVID-19 cases. Most of the confirmed case was male (50.4%) in 19-59 years old (66,7%). The most presented symptoms were cough (78,5%), fever (51,5%), and shortness of breath (37%). Among the confirmed cases, 1076 cases were treated in intensive room (29,12%). We remarkably found majority cases weren’t presented comorbid disease (86,6%). Mortality rate reached to 13% while length of stay more than 14 days seized 23,8%. We performed hospital-based surveillance as a quick response to brand new emerging disease, covid-19. A quick and simple screening was needed for rapid case detection and prevent advance transmission. Hospital-based surveillance was also required to project health care capacity.

Abstract : The COVID-19 pandemic had a dramatic effect on health, economic growth, employment, and way of life worldwide. To measure the effect of the coronavirus oandemic on STIs in public healthcare, multiple studies have been carried out concerning key elements, such as: challenges and management. To review literature focused on studies in global and national aspects concerning initiatives in public healthcare to curb the coronavirus pandemic and at the same time have an effect on the levels of sexually transmissive infections. A review of studies has been carried out for the period January 2020 - November 2022 in databases PubMed, and Google Scholar, as well as data from international and national platforms with the following keywords: “COVID-19”, “STI”, “Challenges”,” Management”. The review outlines the conceptual framework of the issue on a global level. The majority of authors take into consideration major points such as management and challenges to them concerning the coronavirus pandemic and STI. Major challenges to the management of the most common STI in relation to the COVID-19 pandemic and the measures for curbing it have been presented and discussed. The global COVID-19 pandemic and STIs have their intersection point consisting of significant effects on the prevention, therapy, and monitoring of these diseases. At the same time, there are no sufficient studies on the topic about lower-income countries, аnd high-risk social groups.

Abstract : Postoperative pain is a complaint that must be effectively managed. Various analgetic methods are implemented to alleviate open cardiac surgery for postoperative pain, but none of the methods is ideal for managing postoperative pain. Erector spinae plane block is a new technique in open cardiac surgery for postoperative pain. This study aims to determine the difference in post-open cardiac surgery pain measured by using the VAS pain scale in patients with erector spinae plane block and parasternal block. The study was conducted in June-November 2021 in Hasan Sadikin General Hospital, Bandung. This was a single-blind control trial in thirty patients. Patients were divided into two groups, a parasternal block group (group A, n=15) and an erector spinae plane block group (group B, n=15). Postoperative pain was measured by using the VAS pain scale on hours 0-1, 1-6, 6-12, and 12-24. Numerical data were analyzed by using the unpaired T-test and the Mann-Whitney test. Categorical data used the Chi-Square test. ESP blockade has higher effectiveness than a parasternal block in managing pain after open cardiac surgery.

Abstract : COVID-19 infection can progress to severe pneumonia, pulmonary edema, acute respiratory distress syndrome, or multi-organ failure. A severe inflammatory response contributes to the clinical manifestations of patients with COVID-19. Therefore, circulating biomarkers such as C-Reactive Protein (CRP) Value, Total Lymphocyte Count (Tlc) can represent inflammation which can be a good predictor for the prognosis of COVID-19 patients. This study aims to determine the Relationship Between C-Reactive Protein (Crp) Value, Total Lymphocyte Count (Tlc), Lung Compliance And P/F Ratio In Critical Covid-19 Patients With Mechanical Ventilators In ICU. This research is a descriptive observational study with a cross sectional design (cross-sectional). The method used in this study is diagnostic analysis by assessing sensitivity, specificity, positive predictive value and negative predictive value. Data retrieval was carried out retrospectively which was taken from tracing data documents of COVID-19 patients who were treated in the ICU of RSUP Dr. Hasan Sadikin. Low levels of lung compliance are known to predict the length of stay in the ICU but cannot predict the mortality rate of critically ill COVID19 patients. There is a significant relationship between the value of C-Reactive Protein (CRP), Total Lymphocyte Count (TLC), Lung Compliance and P/F Ratio with the prognosis of critically ill Covid-19 patients in the ICU Dr. Hasan Sadikin.