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Abstract : Periimplantitis is an inflammatory disease affects the tissues around functional and well osseointegrated implant. Nevertheless, the bone resorbation may arise due to multiple other factors like implant position, bone density, implant geometry, micro-gap and poor oral hygiene. Saving the implant after it lose a considrable amount of bone is usualy chalenging and in many times the failure of the implant is inevitable. This case report describes the diagnosis and the mangement of a failed unloaded anterior implant using Allogenic Bone Graft in a 28-year-old male with one year follow up.

Abstract : One of the ingredients that is believed to stimulate the formation of dentinal bridges is calcium hydroxide, but this material is highly toxic, the dentinal bridge that forms is porous. Therefore, alternative materials are needed to be biocompatible, such as clam shells which contain calcium carbonate that’s used as a remineralization material for hard tooth tissue. Transforming Growth Factor β (TGF-β) has a significant role in cellular signaling for odontoblast differentiation and stimulation of the dentin matrix. This study aims to determine the expression of TGF-β1 after applying green shell extract paste (Perna viridis) in inflamed Wistar tooth pulp. This research is a laboratory experimental and clinical trial research with a posttest-only control group design with 24 Wistar samples. The experimental animals were divided into 4 groups, namely: negative control, positive control group (CaOH2 application), 1st group (35% green shell extract paste), 2nd treatment group (40% green shell extract paste), be sacrificed within for 3, 7 and 14 days. Data were analyzed on experimental animals using immunohistochemical examination using ELISA. The normality test using the Shapiro-Wilk shows a significant value (p>0.05). Statistical test results using test-independent samples t-test show a value (p<0.05). Based on observation times of 3,7 and 14 days, a higher increase in TGF-β1 expression was seen after the application of 35% and 40% green shell extract paste based on histological examination and statistical tests (p<0.05). Green shell extract paste (Perna viridis) 40% and 35% significantly has higher effectiveness as dental pulp protection agents with increased TGF-β1 expression.

Abstract : Bone is a metabolically active tissue that undergoes continuous regeneration, namely formation and resorption of bone. Bone regeneration is essential for bone homeostasis. Bones must be in constant condition, which is important for the maintenance of normal skeletal structure and function. Food ingredients are needed that can help maximum bone growth, such as anchovies. Anchovies are a source of calcium which is needed in the formation and regeneration process of bones. To determine the potential of anchovy (stolephorus sp.) for mandibular bone regeneration through BMP2 expression. The type of research is laboratory experimental with a posttest only control group design. with a total sample of 27 male Wistar rats (rattus norvegicus) divided into 3 groups. Testing the effectiveness of bone regeneration in experimental animals through immunohistochemical examination using the ELISA technique. The research results were analyzed statistically with a normality test using the Shapiro-Wilk test showing a significant value (p>0.05) meaning the data was normally distributed. The results of statistical tests using the independent sample t-test showed a value of (p<0.05), which means there was a significant difference in BMP2 levels in the anchovy group and the negative control group, but when compared between the anchovy group and the positive control group, it showed no difference in BMP2 levels. significant with a value (p>0.005). Giving anchovies can increase mandibular bone growth in the treatment group. There is a positive correlation between giving anchovies and the amount of BMP2 expression. Further research using different doses and other types of measurements needs to be carried out to determine the potential for mandibular bone regeneration.

Abstract : The coronavirus has disrupted pregnancy plans and increased anxiety among many expectant mothers, who are questioning the impact of the virus on their baby's birth. Therefore, it is expected that support from the social environment can reduce anxiety in pregnant women when choosing a birth attendant during the pandemic. The objective of this study is to analyze the influence of anxiety levels and family support on the choice of birth attendant during the Covid-19 pandemic. The study utilizes a quantitative observational design with a cross-sectional approach. It was conducted from November to December 2021 at Bontomarannu Community Health Center in Gowa Regency, with a sample size of 32 pregnant women selected through purposive sampling. The research results, using the chi-square test, show that anxiety levels have a p-value of 0.007 and family support has a p-value of 0.003 (a<0.05). This means that there is a relationship between anxiety levels and family support with the choice of birth attendant during the Covid-19 pandemic. Anxiety and family support during pregnancy have an impact on the choice of birth attendant during the Covid-19 pandemic.

Abstract : Changes in alveolar bone dimensions following tooth extraction over time are inevitable. Bone resorption and poor bone quality make the placement of dental implants difficult. Oral health care procedures around implants become more difficult and the result is poor both cosmetically and functionally. Therefore, several methods and techniques aimed at reducing or preventing bone resorption, preserving socket, and improving the quality of regenerated bone include autografts, allografts, xenografts, growth factors, and biomaterials. Bone morphogenetic proteins (BMPs) belong to transforming growth factor beta (TGF-β) and are biological factors that play important roles in bone formation process and can significantly increase bone regeneration and, as a result, can be used to preserve alveolar bone after tooth extraction. Evaluate the effectiveness of applying rhBMP-2 locally in order to maintain alveolar bone dimensions after dental extraction, and evaluate the density of bone formed at the extraction site after applying rhBMP-2 using CBCT. Written consent was obtained from each patient who had an indication for bilateral tooth extraction in the same jaw and the same number of roots on both sides. Then, sterilization of the oral fossa, local anesthesia, and separation of the connective ligament from the teeth to be extracted were performed. Then the teeth to be extracted were removed using root levers and clamps with as little trauma as possible, and then the tooth to be extracted was applied. After that we choose a side to apply Gelfoam impregnated with rhBMP-2 liquid (right side or left side) in a simple random manner by withdrawing a paper specifying the study side and in the corresponding control side we applied Gelfoam alone as a hemostatic agent. after which suturing was performed on the extraction sites in both groups, then an x-ray image was taken using cone beam computed tomography. CBCT after the surgical procedure. The use of rhBMP-2 to preserve the socket after extraction reduced the amount of bone resorption that occurred after extraction, both horizontally and vertically, after a follow-up period of three months, but did not completely prevent it from occurring. Using it to preserve the socket immediately after extraction did not significantly improve radiographic bone density compared to the control group in which Gelfoam was applied alone as a hemostatic agent after a follow-up period of three months.