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Abstract : Dengue fever still occurs in many communities every year, so it needs to be prevented. The research objective was to determine the effect of education on mothers' knowledge about DHF prevention. The sample consisted of 40 mothers who were willing to take part in education in Bandung area. Statistical test using the Wilcoxon Sign Rank Test. The results of the study showed that there were significant differences in mothers' knowledge before and after education. It is necessary to carry out health education about DHF on a regular basis to prevent and improve people's behavior in efforts to prevent DHF.

Abstract : This study aims to reveal the results of the needs analysis on the development of classroom innovation models to enhance student convenience in learning. The approach Method and Type of research used is Research and Development (Research and Development: R & D) using Bord and Gall's development concept. The data analysis techniques used to process the data are content analysis and descriptive analysis. This study indicates that creating learning convenience is necessary to make breakthroughs in managing learning process facilities. The objective is to increase convenience in the teaching and learning process by integrating outdoor and indoor classes in classes that collaborate with nature, and free air collaborates with beautiful gardens.

Abstract : To find out the outcome of preterm labour perinatal morbidity and morality Methods A prospective cross-sectional study conducted and OG department from Jan 21-dec21 GVMCH by random sampling method 100 subjects less than 37 weeks with cervical length less than 2 cm with multiple pregnancy, chronic, HTN, DM, Thyroid disease, UTI, bacterial vaginosis were subjected to complete obstetrics work up including history general physical examination, systemic examination and relevant lab investigation. patient with preterm labour the hospitalized and treated with antibiotics, corticosteroids and tocolytics and Mgso4 for neuroprotection Observation were entered in Excel and study using SPSS software. Majority of study population are in B/W the age group of 20-25 years. Majority of participants are in B/W 32-37 weeks gestational age. Among them 72% population belongs to low society economic claims. BMI B/W 18.5-24 are mostly involved. IUGR was noted. The neonatal morbidity and morality in preterm depends on the gestational age at admission the time B/W on set of labour pain to delivery in our study with administration of antenatal steroids + MgSO4 in patients with threated pre-term delivery brings out better neonatal outcome then compared to patients delivered without steroids.

Abstract : Cancer cervix accounts for 6.29% of cancer in women in India. Aim of this study is to prove the diagnostic efficacy of the colposcopy by correlation between Reid’s Colposcopic index and histopathological report of CIN. This non-randomized study done for one year in IOG and 180 –KGH by convenience sampling. All women with VIA/VILI positive were subjected to colposcopy. The margins of atypical cervical epithelium are graded and assessed with iodine staining Reid’s scoring based on all findings was made. Colposcopy detailed biopsy was taken. The sensitivity, specificity and predictive values were calculated with diseases threshold of CIN 1 as well as CIN 2. About 166 women had participated. 83 women (51.8%) belonged to 41-60 years. 58.1%women had 2 living children. premenopausal (87) and postmenopausal (73) were almost equal. 56 women had postmenopausal bleeding, 45 had HMB and 87 women had white discharge. RCI findings were 45(28.1%) benign, 53(33.1%) had CIN, 39 (25.4%) had CIN 2 and 23(14.4%) had CIN 3 the biopsy findings were 49(34.4%) benign, 55(34.4%) had CIN 1 29(18.1%) had CIN 2 17(16.2%) women invasive carcinoma the level of agreement between colposcopy RCI and biopsy findings using kappa statistics was 72% (P-0.045). spearman correlation was 0.85 (P<0.001) ROC showed 91.9% sensitivity 73.5%specificity, 80% PPV and 88%NPV. There is high sensitive and specificity with 72% agreement of biopsy finding, colposcopy RCI has good correlation with determination of CIN. Hence it is a reproducible technique which is easy to implement in colposcopy clinics.

Abstract : Mercury chloride can cause nephrotoxicity, increase ROS, MDA, and decrease TGF-β resulting in tubular cell membrane damage. The metallothionein protein found in IR Bagendit rice leaves can bind mercury and coconut water contains lots of antioxidants. The aim of this study was to find out how the infusion of IR Bagendit rice leaves and coconut water improves kidney damage. The experimental study on Rattus nurvegicus rats used in the experiment was divided into five groups: negative, positive control, and treatment 1, 2, and 3. Each group contained six rats. The negative control group was given only a placebo. The positive control group received a daily dose of HgCl2 20 mg/day/kg BW. Treatments 1, 2, and 3 each received 0.2 ml, 0.4 ml, 0.8 ml of water extract of rice leaves of IR Bagendit and coconut water up to 4 ml/100 g BW, all treatment groups were exposed to mercury chloride 20 mg/kg body weight per day. All groups had their blood and kidney organs taken on the 15th day. ROS, MDA, TGF-β levels using Elisa, urea, and creatunu using enzymatic. Renal tubular necrosis and degeneration using HE staining. The results showed that when compared with the positive control group, the average ROS, MDA decreased, the average TGF- increased, and the average cell degeneration and cell necrosis decreased. The average levels of urea and creatinine are still within normal limits. In conclusion, rice leaf water extract can improve the morphology and function of kidney cells in Rattus nurvegicus exposed to HgCl2.