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Abstract : Hemolysis and regular blood transfusions as the long-term beta thalassemia major treatment can cause iron accumulation and damages these organs, potentially causing death. Iron accumulation in the heart muscle decreases ventricular function and may progress to cardiomyopathy and heart failure. Serum ferritin concentration can determines iron stores in the body. Heart failure can be indicated by cardiac markers, such as troponin. This research was an analytical cross-sectional study conducted to observe the relationship between serum ferritin and troponin I levels in children with beta thalassemia major receiving blood transfusion, particularly at Haji Adam Malik hospital, Medan, Indonesia. Univariate analysis was used to asess the mean levels of serum ferritin and troponin I. Bivartiate analysis was used to assess the relationship between serum ferritin level and troponin I level, where Pearson correlation test for normal distribution data or Spearman correlation test for abnormal data distribution. The mean serum ferritin level was 7233.26 ng/mL. The majority of the research subjects had serum ferritin level above 1000 ng/ml. There was only 1 child (1.5%) with serum ferritin level below 1000 ng/mL. The mean troponin I level was 5.97 ng/mL. Almost two third (41 / 62.1%) of the research subjects had troponin I level above 0.8 ng/mL, while the remaining research subjects (25 / 37.9%) had troponin I level below 0.8 ng/mL. There was a significant relationship between serum ferritin level and troponin I level in children with beta thalassemia major at Haji Adam Malik hospital, Medan, Indonesia (p <0.001).

Abstract : The prevalence of stunting in Indonesia in 2020 is 31.8%, in 2021 the province of Maluku the prevalence of stunting under five is 28.7%, and the prevalence of stunting in Ambon city is 21.8%. The aim of this research is to find out the dominant factors that cause stunting. The research was conducted at stunting intervention locations (Laha Village, Poka Village and Rumah Tiga Village) in Ambon City. The research design is a case control study. The total sample was 212 toddlers aged 24-59 months, consisting of 106 stunting cases and 106 respondents who were not stunted. Sampling was done by systematic random sampling. Data were analyzed using Multiple Logistic Regression with predictive models and the Confounding test by calculating the OR of changes using the Cochran-Mantel-Haenszel formula. The results of the Multiple Logistic Regression / multivariate test show that the factors that cause stunting are the most dominant variable Recurrent infection with diarrhea and/or ISPA after being controlled by the mother's ANC quality variable, Exclusive breastfeeding, and smoking behavior at home, value (OR 3.74).General population 95% of researchers believe that Recurrent infection with diarrhea and/or ISPA Iis a risk factor for stunting events with a range of intervals (1.84 to 7.61).

Abstract : Muscle pain is the most common ergonomic complication due to the use of trolleys. Trolleys with a hydraulic system can reduce complaints of muscle pain experienced by hospital laundry staff. The study aimed to add a hydraulic system to the hospital laundry trolley to reduce complaints of muscle pain and to add hand hygiene facilities in the form of hand drubs, and glove containers to avoid cross-infection when transporting linen. The study was quantitative with a cross-sectional approach. The 7 respondents involved in this study were determined by total sampling. Data were collected using the Nordic Musculoskeletal Questionnaire before using the hydraulic system trolley and 1 month after using it. Data were analyzed using paired t-tests. The results showed that the use of a hydraulic system trolley was effective in reducing muscle pain in complaints of slight aches and pains (p<0.05) and less effective in complaints of very pain if the respondent had comorbid complaints of musculoskeletal disorders (p=0.38 where p>0.05). The Linen-Laundry Unit can use a hydraulic system trolley to reduce muscle pain in linen management which includes collecting dirty linen, transporting linen, and distributing clean linen.

Abstract : Malaria is one of the parasitic infectious diseases that is still a public health problem, including in Indonesia. Southwest Sumba District in NTT Province has been classified as a high endemic malaria area with dihydroartemisinin-piperaquine (DHP) as an antimalarial since 2004. One of the problems in malaria elimination has been the treatment failure due to plasmodium resistance to antimalarial drugs. This research was conducted in January-December 2019 in the North Kodi sub-district, Southwest Sumba District, NTT Province. This study used the prospective cohort design to determine the efficacy of DHP in people with uncomplicated falciparum malaria. Two hundred thirty-three patients with uncomplicated falciparum malaria were enrolled in the study. The treatment failure was 3.9% (95% CI: 1.3-10.8), categorized as 3% ETF and 0.9% LPF. Ten patients (4.3%) were still positive on day-2. The patients still positive for malaria falciparum can be found until day-21. There is no correlation between the number of parasites and body temperature on day 0 (r =-0.0352,p-value = 0.595). The PCR uncorrected on day-42 ACPR was 96.1% (95%CI: 92.8-98.2). The results confirmed that the efficacy of DHP is still in accordance with WHO criteria and can still be used as malaria therapy in Southwest Sumba Regency. This study add information on the Efficacy of DHP from another high malaria-endemic area in Indonesia. Information on the Efficacy of DHP outside Papua is limited, and the result of this study can add information to the policy on malaria treatment in Indonesia.

Abstract : The background of this research is the problem of the non-optimal performance of nurses at RSHS Bandung. The indications that are the cause of this are several factors in organizational culture, compensation, and motivational variables that still need to be optimal. The purpose of this study was to analyze to obtain information regarding the influence of organizational culture and compensation on motivation and its impact on nurse performance. Respondent Data collection was carried out by distributing questionnaires to 152 nurses using a proportional random sampling technique. Data processing was performed using SPSS and analyzed using path analysis. The results of this study state that organizational culture and compensation have a significant effect on giving motivation both partially and simultaneously, with the coefficient of determination of organizational culture on giving motivation of 52.9% and compensation of 14.5% on giving motivation. In addition, providing motivation significantly affects nurse performance, with a coefficient of determination of 67.4%. Organizational Culture has a significant effect on giving motivation, Organizational culture and compensation significantly affect nurse motivation, organizational culture and compensation significantly affect giving motivation, and Giving motivation to nurses significantly affects nurse performance.