Search Results

Abstract : The primary objective of this research was to evaluate the effectiveness of hypnobreastfeeding in enhancing breast milk production, infant growth, and maternal hormonal changes. This research was a quasi-experimental study conducted at the Regional Hospital Koesma in Tuban, Indonesia. The study spanned 12 months and involved 80 postpartum women, divided into two groups: a treatment group receiving hypnobreastfeeding sessions and a control group receiving standard postpartum care. Key metrics for the study included demographic data, levels of dopamine, Thyrotropin-Releasing Hormone (TRH), and Prolactin (PRL), breast milk volume, and infant growth, as measured by the Denver Developmental Screening Test II (DDST II). The study observed significant hormonal changes post-intervention in the treatment group. There was a marked decrease in dopamine levels (58±16.34) and an increase in TRH (24.55±47.91) and PRL (482.92 ng/ml±596.6). Additionally, the treatment group exhibited a notable increase in breast milk production and enhanced infant growth compared to the control group. Specifically, breast milk volume and infant weight in the treatment group were significantly higher, especially evident in the 1-6 month period post-intervention. The findings of this study suggest that hypnobreastfeeding is a beneficial intervention for breastfeeding mothers, significantly impacting breast milk production and infant growth. The hormonal changes observed in the treatment group further support the efficacy of hypnobreastfeeding. These results highlight the potential of hypnobreastfeeding as an effective practice for breastfeeding mothers, paving the way for further research into its comprehensive impacts on maternal and infant health.

Abstract : Cyclophosphamide(CTX) is an alkylating chemotherapeutic drug with immunosuppressive activities. It is a toxic drug which targets both the cancer cells and also the normal cells. The objective is to study the dose at which harmful effects of CTX are caused on testes, liver and kidney tissues. A total of 55 male Wistar rats were divided into eleven groups comprising 5 animals each. Animals in group 1 (control group) were given 1.5mls Phosphate Buffered Saline (PBS) solution weekly for 4weeks. Animals in groups 2-11 were given CTX at 25.1, 50.2, 75.3, 100.4, 125.5, 150.6, 175.7, 200.8, 225.9, 250.0mg/kg body weight orally weekly for 4weeks. They were then sacrificed 4hours after administration on the fourth week. The testes, liver and kidney tissue were processed, sectioned and stained with H&E. Significant pathological changes were seen after 4weeks. The changes were more prominent as the dosage of CTX administered increased. These pathologies ranged from mild to severe atrophy of spermatogonic epithelium with or without preponderance of round spermatids in the lumen, moderate to random periportal fibrosis with centrilobular cord atrophy and pyknosis of hepatocytes, atrophy of tubular epithelial cells with severe interstitial inflammation and tubular epithelial necrosis. The pathological changes were observed in the histology of testes, liver and kidney following increase in the dosage of treatment among groups. Hence, a regular semen analysis and testicular hormonal assay, regular liver and kidney function test are encouraged in patients taking chemotherapeutic agents like CTX with possible concurrent administration of repro-protective, hepatoprotective, and nephroprotective agents.

Abstract : This research is a comprehensive evaluation of the learning environment at the medical college of Tabuk University in 2023. The study seeks to delve deeply into the various facets that constitute the educational experience of medical students, recognizing that the environment in which they learn is crucial to their development as future healthcare professionals. At its core, the research explores the dynamic interactions between teachers and students, assessing how these relationships contribute to or hinder the learning process. It also examines the effectiveness of the teaching methods employed, considering whether they stimulate intellectual curiosity and foster a deep understanding of medical concepts. Additionally, the study investigates the support systems in place for students, particularly those who may experience stress or other challenges, to determine how well these mechanisms function in alleviating their concerns and promoting their well-being. The overall atmosphere of the learning environment is another key focus, as it plays a significant role in shaping students' motivation, engagement, and satisfaction with their education. By using a detailed questionnaire, the research gathers and analyzes the perceptions of students regarding these aspects of their educational experience. The goal is not only to paint a clear picture of the current state of the learning environment but also to identify specific areas that may require improvement. Through this evaluation, the research aims to provide valuable insights that can inform efforts to enhance the quality of medical education at Tabuk University, ensuring that it meets the highest standards and effectively prepares students for their future roles in the healthcare field.

Abstract : This study explores medical students' attitudes toward communication skills and the factors influencing these attitudes. It aimed to assess how students perceive the importance of communication skills in their medical education and practice, identify socio-demographic and educational factors affecting their attitudes, and evaluate the impact of these attitudes on their communication training outcomes. Using a survey with 179 medical students, the research found a varied range of attitudes, from strong support for the relevance of communication skills to skepticism about their practical value. Key factors influencing attitudes included gender, native language, and educational level. The study revealed that while some students recognized the importance of communication skills for effective patient care and teamwork, others struggled with the perceived relevance and time commitment of training. The results highlight the need for curriculum adjustments to address these challenges, recommending enhanced integration of communication skills training and tailored educational strategies to improve student engagement and proficiency.

Abstract : Metabolic disorders were a significant health issue for many adults with congenital heart disease, but the variations in metabolite levels related to metabolic syndrome between Asian adults with congenital heart disease and the healthy population were not known. The aim of this study is to compare lipid levels between congenital heart disease patients and control group in Asian adults. This systematic review and meta-analysis was performed according to PRISMA 2020 guidelines. A literature search was conducted through PubMed, ScienceDirect, and Cochrane Library selecting observational studies until July 2024. The studies showed lipid levels in Asian adults with congenital heart disease. Meta-analysis was conducted using R Studio 4.3.2 software. In total, 6 observational studies (4 studies for meta analysis) involving 434 patients with congenital heart disease and 405 controls were eligible for this review. The quantitative analysis showed that patients with congenital heart disease have lower levels of total cholesterol (MD: -2.57 [95% CI: -5.00 to -0.14]; p=0.038), LDL-C (MD: -1.58 [95% CI: -3.26 to 0.10]; p=0.065) and HDL-C (MD: -0.86 [95% CI: -1.14 to -0.58]; p<0.001) compared to controls. Total cholesterol and HDL-C in Asian adults with congenital heart disease were significantly lower than those in the control group. New research should be developed to clarify this relevant topic.