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Abstract : Workload and work stress with fatigue are some of the risk factors for work performance problems. This study aims to determine the effect of workload, work stress’s and fatigue and their impact on the performance of nurses at Dadi Hospital, South Sulawesi Province. The research was conducted at the Dadi Hospital in South Sulawesi Province. This research uses quantitative methods. The population in this stuwasere 233 nurses at the Dadi General Hospital in South Sulawesi Province with 147 nurses used as samples. The type of research in this study is Analytical Observational using Cross-Sectionalal approach and this research uses a Path Analysis model, in which the intervening variable is fatigue which lies between exogenous variables. The data that has been collected is then analyzed through a process of data reduction, data presentation, and drawing conclusions and verification. From the results of the study it can be concluded that 46 respondents (31.3%) experienced heavy workload, 82 respondents (55.8%) experienced moderate work stress, 105 respondents (71.4%) were very tired), and poor work performance of 59 respondents (40.1%). Based on the results of statistical tests using the chi-square test, thp-valueue was 0.007 <0.05, meaning that there is a significant relationship between work stress and fatigue. And based on the results of AMOS work stress affects performance through fatigue (0.011). From the results of the study it can be concluded that 46 respondents (31.3%) experienced heavy workload, 82 respondents (55.8%) experienced moderate work stress, 105 respondents (71.4%) were very tired), and poor work performance of 59 respondents (40.1%). Based on the results of statistical tests using the chi-square test, thp-valueue was 0.007 <0.05, meaning that there is a significant relationship between work stress and fatigue. And based on the results of AMOS work stress affects performance through fatigue (0.011). From the results of the study it can be concluded that 46 respondents (31.3%) experienced heavy workload, 82 respondents (55.8%) experienced moderate work stress, 105 respondents (71.4%) were very tired), and poor work performance of 59 respondents (40.1%). Based on the results of statistical tests using the chi-square test, thp-valueue was 0.007 <0.05, meaning that there is a significant relationship between work stress and fatigue. And based on the results of AMOS work stress affects performance through fatigue (0.011). and poor work performance as many as 59 respondents (40.1%). Based on the results of statistical tests using the chi-square test, thp-valueue was 0.007 <0.05, meaning that there is a significant relationship between work stress and fatigue. And based on the results of AMOS work stress affects performance through fatigue (0.011). and poor work performance as many as 59 respondents (40.1%). Based on the results of statistical tests using the chi-square test, thp-valueue was 0.007 <0.05, meaning that there is a significant relationship between work stress and fatigue. And based on the results of AMOS work stress affects performance through fatigue (0.011).

Abstract : Infant carrying has been reported to be physically demanding with risks of physical challenges to mothers/caregivers. This makes it important to evaluate different Infant Carrying Methods (ICMs) to guide choices for the promotion of maternal health. This study evaluated the effects of four ICMs (A–back, B–front, C–side, and D-in-arms) on trunk muscular activities. Thirty women simulated four ICMs while the electrical activities of the right (Rt) and left (Lt) components of the erector spinae (ES), rectus abdominis (RA), and external oblique (EO) muscles were recorded simultaneously during the tasks. Within-subject comparisons of the muscle activities showed that only the front (p = 0.011) and side (p = 0.033) ICMs elicited significant differences with their highest activities recorded in the left and right EO muscles, respectively. Between-subject comparisons of the muscle activities showed a significant difference (p = 0.022) only in the right EO muscle, being most active during the side ICM. The side ICM was observed to elicit the highest activities in three of the four studied muscles. Side ICM has more potential for over-exerting the trunk muscles, which could be a possible factor for muscular fatigue and resultant musculoskeletal impairments.

Abstract : Osteosarcoma is the most common bone malignancy in children. Osteosarcoma prevalence of 20% of all primary bone tumors in children. This study aims to determine the prevalence of osteosarcoma patients at Prof. Dr. I G N G Ngoerah Hospital. This was a retrospective study used secondary data collected from solid tumor register in Prof. Dr. I G N G Ngoerah Hospital in January 2016 – June 2022. Data from Prof. Dr. I G N G Ngoerah Hospital in January 2016 – June 2022 showed the prevalence of osteosarcoma in children is 30 cases, which the total cases had a greater prevalence in the male sex 18 (60%) and the age group 5 - 14 years amounted to 16 (53.3 %). In nutritional status, the highest prevalence was in good nutritional status 14 (46.7%), the highest location prevalence was in the tibia 12 (40%). Hematological data showed mean WBC 11.18, Std. deviation 5.37. Mean neutrophil 9.18, Std.deviation 12.15. Mean Hb 11.61, Std. deviation 2.71. Mean Plt 329.81 Std, deviation 129.42. Among amputated patient, 3 patients survive (10%), 4 patients died (13%). Among non-amputated patient, 8 patients survive (26%), 24 patients died (80%). Data on prevalence and characteristics are important as basic data in understanding risk factors and prognosis of osteosarcoma. Early detection, prompted management and selective amputation must be conducted to improve survival of the patients.

Abstract : Gastric ulcer is a disease disorder caused by damage to the mucous layer, submucosa, to the muscle layer of the gastrointestinal tract due to the activity of pepsin and stomach acid. This study aims to determine the effect of nutmeg flesh as an anti-ulcer. Tests were carried out using Wistar strain white rats. Nutmeg Flesh Extract (NFE) was obtained by maceration method using 70% ethanol, then divided into three dose groups, NFE 400, 900, and 1800mg/kgbw. Acetosal 500mg/kgbw was given as an ulcer inducer on the 8th day. As a positive control, Omeprazole was used at 20 mg/Kgbw. The test parameters observed were the number of ulcers, ulcer index, % protection, gastric pH, total acidity of gastric juice, and histology of gastric tissue. The results showed that the ethanol extract of nutmeg flesh at doses of 450, 900, and 1800 mg/kgbw had significantly different anti-ulcer activity against negative controls (p<0.05) in acetocal-induced rats with the highest protective ratio indicated by a dose of 1800 mg/Kgbw.

Abstract : The prevalence of stunting in Indonesia 2020 is 31.8%, in 2021 the prevalence province of Maluku stunting under five is 28.7%, and the prevalence stunting in Ambon city 21.8%. the aim of the study was to determinants household factors and environmental factors on the incidence stunting. The research was conducted in Teluk Ambon sub-district, Ambon City. Research is design case control study. Total sample was 228 toddlers aged 24-59 months, consisting of 114 stunting cases and 114 not respondents stunted. Sampling was done by systematic random sampling. Data were analyzed using Chi-Square test and Multiple Logistic Regression. Results of Chi-Square test on the ANC quality variable Mother p=0.001 OR (4.5), KEK p=0.015 OR (1.9), parenting style p=0.041 OR (1.7), Exclusive breastfeeding p=0.000 OR (3.8),children anemia p=0.004 OR (3.3),diarrhea and/or ISPA p=0.000 OR (4.3),smoking in house p=0.000 OR (4.4), education p=0.005 OR (2.4), income p=0.000 OR (3.7), water quality p=0.027 OR (2.0), and basic sanitation p=0.001 OR (2.5) 11 variables show there influence on incidence of stunting and are a risk factor stunting events. Where as immunization history p=0.056 and monitoring of growth development p=0.196 had no effect the incidence of stunting. Test Multiple Logistic Regressionon household determinants the most dominant variable is the quality ANC Mother (OR 3.6 95% CI 1.29 – 10.2) after being controlled. The most dominant environmental determinant is basic sanitation (OR 2.5 95% CI 1.48 – 4.31). For household and environmental determinants, the most dominant variable ANC quality Mother (OR 3.6 95% CI 1.29 – 10.2) after being controlled.