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Abstract : Lipoprotein (a) [Lp[a]] is a particle containing apolipoprotein bind to LDL cholesterol. Lp(a) encoded by LPA gene. Independent from LDL-C level, raised Lpa level by genetic studies shows increasing risk of cardiovascular disease. Prior study shows most of patient with LDL-C controlled by statin still have raised Lp(a) level. Current therapy to lowering LDL-C, could not achieve expected lowered Lp(a) level. Genetic therapy as a novel treatment for lowering Lp(a) is still under investigation. We review several study about Lp(a) correlation with LDL-C, coronary disease, and novel treatment. Most of genetic therapy give promising effect although still under early clinical trial. Prior lipid lowering treatment did not achieve as high as genetic therapy to lowering Lp(a) level.

Abstract : This aim research was to determine the effect of spiritual distraction therapy in reducing chronic joint pain among elderly living in coastal area. This study was quantitative with quasi-experiment and pre-post-test control group design. The number of respondents was 70. Spiritual distraction therapy was given during seven days. The data collection used observation sheet which contain PQRST pain assessment and the VAS pain scale. Statistical test using the Wilcoxon and Mann-Whitney tests. The study results of the Wilcoxon rank test showed that there was a significance difference in pain area (p-value<0.000) and the time of pain (p-value <0.000) in the treatment group. The Mann Whitney test results showed that there was a significance difference between control and treatment group in pain area (p-value=0.038) and the time of pain (p-value=0.45). The spiritual distraction therapy was effective in reducing the pain area and time of pain occurrence of joint pain in the elderly who live in coastal area. Further study needs to explore the effect of spiritual distraction on pain in other population.

Abstract : Neonatal mortality has been reported as a major societal health menace across the globe. Hence, this study, which adopted a hospital-based cross-sectional type of experimental research design, aimed at examining the clinical indication of some selected cardiopulmonary and anthropometric indices as key predictive clinical biomarkers for neonatal survival. The subjects were divided into three groups; experimental Group 1 consisted of 80 pre-term neonates within 28 weeks; experimental Group 2 consisted of 80 pre-term neonates within 33 weeks; and the control group, which consisted of 80 apparently healthy, term neonates. For each subject selected, cardio-pulmonary parameters and anthropometric variables were obtained daily and compared. ANOVA, correlation coefficients, and linear regression were used to compare statistical measures. A discrimination accuracy test of previous records using cut points available from previous models was conducted for ease of estimating the possibility of neonatal survival from assayed variables. Following data collection, sorting, and analysis, the study found a statistically significant decrease (p < 0.05) in average systolic blood pressure (SBP) values of preterm neonates when compared with term neonates. This, however, was the reverse for DBP, which was proved to have increased in preterm neonates compared to term neonates. The study also observed a statistically significant decrease (p < 0.05) in RR and OSL levels of preterm neonates compared to term neonates. In conclusion, cardiopulmonary and anthropometric status could be useful predictive biomarkers in clinical trials to provide insight into the extent of compromise in newborn health. This will help to minimize the death of neonates by ensuring a better treatment protocol/regimen is given. A corroborative study with an event-driven approach that assays more molecular or other non-physiological variables is recommended.

Abstract : The current study was conducted in Diyala Governorate during the period from 20/4/2021 to 20/8/2021 on women who had aborted and non- abortive women. A questionnaire was prepared to collect information on each case included in the study. The examination was conducted on 250 serum samples using a latex test, the highest abortion rate was recorded in the age group 26-30 years, with a rate of 31.57%. There are significant differences at the level of P≤0.05. The incidence was higher in the city, at 64.63% and the highest rate was recorded in the middle-income group, at 54.87%, and it was higher among housewives, at 75.60%. It was also noted that the infection rate was higher among women who suffered from first period miscarriage, 46.34%. Either the abortion stage was higher during the trimester the first pregnancy a rate of 60.97%. There are significant differences at the level of P≤0.05. Nine cases of IgM positive for aborted women were recorded out of 250 cases, at a rate of 3.44%, and the highest percentage appeared in the age group of 21-25 years, and it amounted to 5.71%. The highest rate of infection was in the age group 26-30 years, amounting to 31.57%. 5 cases were recorded positive for both IgM + IgG antibodies out of 250 cases, at a rate of 1.88%, and the highest rate of abortion was recorded in the age group 21-25 years, which amounted to 2.85%. The study showed a high percentage of IgG antibody compared to IgM antibody ratios for both abortions when the diagnosis was made by latex test.

Abstract : Eating disorders (EDs) are associated with a significant risk of comorbid psychiatric conditions and medical complications along with high mortality rate and suicide risk. This study aimed to assess psychiatry residents’ knowledge and attitudes toward eating disorders. This descriptive cross-sectional study was conducted among psychiatric residents in Saudi Arabia. A self-administered questionnaire was distributed electronically to psychiatric residents through the Saudi Commission for Health Specialties database. The questionnaire collected demographic information (e.g., age, sex, and nationality), previous experience with eating disorders, and assessment of knowledge of and attitudes toward eating disorders. Fifty-two psychiatric residents (65.4% men, 34.6% women) were included in this study. Most participants (65.4%) belonged to the 20–30-year age group, and 46.2% of all participants were service residents. Knowledge of eating disorders was poor among 63.5% of residents and good among 36.5% of residents. There was a positive attitude toward eating disorders among 76.9% of residents, while 21.3% showed a negative attitude. The younger age group (age <35 years) showed significantly better knowledge, Saudi nationals, training residents, and those with ≤4 years in psychiatric practice; however, there was no difference in their attitudes. While psychiatric residents had an optimistic attitude toward eating disorders, they lacked knowledge of eating disorders. Among all participants, young Saudi trainee residents who were at an early stage of their career had better knowledge than those in the other groups.