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Abstract : Infection and a lack of micronutrients are what prevent plants from thriving in toddler. The reason of this find out about was once to analyze infection and micronutrient supplementation on the Z rating of young people with failure to thrive. An experimental with Pretest Posttest Group Design was carried out on sixty-nine children aged 12-23 months who, for two months, were observed to gain less than the 5th percentile of WHO standard weight increment, selected with the aid of consecutive sampling and stay in the coastal area of the city of Semarang. The supplementation intervention was given to three groups in a double- blind manner: 1) Zn sulfate syrup 10 mg; 2) iron syrup 7.5 mg + vitamins B complex; 3) Zn sulfate syrup 10 mg and iron syrup 7.5 mg + vitamins B complex. The research was once carried out for two months. The lookup instrument used a questionnaire, baby scale, infantometer, WHO Antro, nutrisurvey. Statistical test using paired T-test, multivariate analysis of variance, and dummy variable logistic regression. The Paired T-Test confirmed that there used to be a sizable difference in the Z Score in WHZ in the two supplementation groups (p=0.014). The MANOVA test concurrently for the three groups affected the Z Scores of WAZ, HAZ and WHZ (p=0.001). Post Hoc evaluation determined that the Z score of WHZ in group two used to be one-of-a-kind from team 1 (p=0.001) and group 3 (p=0.011). Micronutrient supplementation influences the Z Score of WHZ in children who fail to thrive. The Dummy Variable Logistic Regression found that the incidence of URI affected WHZ.

Abstract : Symptoms of allergic rhinitis (AR) in the form of sneezing, runny nose, stuffy nose, and itchy nose which are chronic, progressive, irreversible in advanced stages can cause sleep disturbances. Allergic rhinitis can be assessed subjectively by assessing the symptoms that appear using the Total Nasal Symptom Score. Sleep disturbance can be assessed subjectively by analyzing the level of daytime fatigue using the Epworth Sleepiness Scale questionnaire. This study aims to find the relationship between the Total Nasal Symptom Score and the Epworth Sleepiness Scale in allergic rhinitis patients. This type of research is analytic observational with a cross sectional study design. The research sample was AR patients who had been treated at URJ ENT-BKL RSUD Dr. Soetomo Surabaya in the period 1 January 2019-31 December 2021 (n=115). Baseline data, TNSS, and ESS were obtained using a google form questionnaire. The collected data was filtered using exclusion criteria and then statistically analyzed using the Spearman correlation test. The two patients with normal TNSS were all known to have normal ESS. Fifty-two patients with mild TNSS were all found to have normal ESS. Forty-two patients with moderate TNSS were found to have normal ESS values of 47.62%, mild ESS of 23.81%, moderate ESS of 28.57%, and no severe ESS. Nineteen patients with severe TNSS did not have normal ESS, while 15.79% of mild ESS had mild ESS, 26.32% moderate ESS and 57.89% severe ESS. The Spearman correlation test results from the research data showed a significant relationship (p = 0.000), with a positive correlation and a strong correlation level (r = 0.785). There is a strong positive relationship between TNSS and ESS in AR patients.

Abstract : Excessive salt consumption has been shown to increase blood pressure and increase the prevalence of hypertension. Recommendations for the use of sodium (Na) should be no more than 2 grams/day (equivalent to 5-6 grams of NaCl per day or 1 teaspoon of table salt) (inaSH, 2021). The incidence of hypertension, especially in coastal communities, is caused by diet and lack of physical activity. Meanwhile, in the Baubau City area in 2020, there will be 4,822 hypertension sufferers (56.5%). Whereas in 2021 there will be an increase of 6,359 cases. Cases of people with hypertension in Baubau City currently rank first among the 10 highest diseases after Common Cold. The study aimed to determine the risk of salt consumption on the incidence of hypertension in communities in the coastal area of Baubau City. The method that the researcher uses is an analytic observational study with a Case-Control study design. Case-Control is a research method by comparing the case group (people who suffer from hypertension) and the control group (people who do not suffer from hypertension). Sampling was done by purposive method sampling. Data were obtained directly from respondents who were selected as research samples through interviews using questionnaires and measuring blood pressure. The results of this study indicate that there is a risk of salt consumption with the incidence of hypertension in people in the coastal area of Baubau City. The results of the study indicate that there is a risk of salt consumption with the incidence of hypertension in people in the coastal area of Baubau City. It is hoped that the Baubau City Health Office will direct each Community Health Center to provide education regarding restrictions on consuming salted or salted food.

Abstract : Vulvovaginal candidiasis (VVC) is an infection of the lower female reproductive tract mucosa caused by the polymorphic opportunistic fungus Candida albicans. Colonization of C. Albicans in the vaginal lumen is generally asymptomatic. Vulvovaginal candidiasis (VVC) is a common infection of the genital tract that affects millions of women worldwide. This study aims to determine the effect of methanol extract of Bajakah (Spatholobus littoralis hassk) on the morphology of Candida albicans in the vagina of female rats (Rattus norvegicus) Vulvovaginal Candidiasis model. This study used a quantitative approach, namely a simple experimental design (actual trial) with a completely randomized design method, and the posttest-only control group design approach was chosen. Examination of the hyphae of the fungus Candida albicans was carried out using a qualitative descriptive design approach, which describes, describes, and describes the object under study. The results showed that there was an increase in serum levels of IL-10 in the blood of KVV model rats by administration of pirated extract in each treatment group (P1, P2, and P3) which showed the mean respectively: P1 136.609 pg/mL, P2 147.212 pg/ mL, and P3 148.270 pg/mL with a p-value of 0.021 and this study also showed that there was an effect of giving piracy extract in various concentrations on serum IL-10 levels, that is, the more concentrations used, the serum IL-10 levels increased. Administration of various doses of methanol extract of Bajakah (Spatholobus littoralis hassk) did not affect the decrease in the morphology of Candida albicans in the vagina of female rats (Rattus norvegicus) Vulvovaginal Candidiasis (KVV) model, in this case, the number of hyphae microscopically did not increase or decrease with increasing concentration of the extract.

Abstract : Hemophilia is a congenital disease resulting from a severe coagulation factor VIII or factor IX deficiency. This condition causes the emergence of target joints, which in 30% of hemophilic patients develops hemophilic arthropathy. We reported three cases of hemophilic arthropathy that were examined using conventional radiology modalities, ultrasound and 1.5T MRI at Dr. Kariadi Semarang. Conventional radiological examinations were assessed using the Arnold Hiltgartner qualitative scale and the Petterson quantitative score. The first case was an 11 years old child with type B hemophilia, and right knee pain with an Arnold Hiltgartner scale of 4 and a Petterson score of 7. An MRI examination obtained an IPSG MRI score of 7. The second case is an 8 years old child with hemophilia type B who complains of a swollen right knee. On examination, the Arnold Hiltgartner scale was 4, and the Petterson score was 7. The results of the ultrasound examination showed a HEAD-US score of 6. The third case is a 28 years old man with hemophilia type A and right knee pain, with an Arnold Hiltgartner scale of 5 and a Petterson score of 12. In conclusion, conventional radiography is a sensitive initial examination for moderate and severe degrees of hemophilic arthropathy. Ultrasound modality is an effective follow-up examination in assessing soft tissue abnormalities and osteochondral changes, while MRI has the best sensitivity for detecting hemophilic arthropathy.