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Abstract : About 4-8% of women of reproductive age suffer from polycystic ovary syndrome (PCOS), also known as Stein-Leventhal syndrome, a diverse endocrine condition. Research the impact of Plantago major leaves extract on the induced polycystic ovarian syndrome in rats, assess the impact of Plantago major leaves extract on biochemical markers (Adiponectin and serum blood glucose), and examine the impact of Plantago major leaves extract on hormones (FSH, LH, testosterone, and estrogen), and contrast the impact of Plantago major leaves extract with that of metformin. Female rats were treated for 21 days with 0.4 mL of oral letrozole (5.3 mg/kg) before receiving a dose of Metformin (500 mg/kg) for the first group, a high dose of Plantagomajor (1500 mg/kg) for the second group, a low dose of Plantagomajor (1000 mg/kg), and a combination of Plantagomajor (500 mg/kg) and metformin (250 mg/kg) for the third group. Compared to the induction group, the plantagomajor treated group had reduced levels of glucose, testosterone, and LH, but higher levels of adiponectin, estradiol, and FSH. In comparison to metformin, plantago major treatment groups saw greater effects in terms of easing PCOS symptoms in female rats.

Abstract : Rhino-orbital Mucormycosis is an opportunistic fungal infection affecting mainly diabetic and other immunocompromised patients. Covid-19 infection has augmented the risk of mucormycosis cases due to use of steroids or due to immunosuppressed condition because of infection itself. In the present study four cases with rhino-orbital mucormycosis have been presented. They were etiologically diagnosed as Mucorales by KOH mount and fungal culture. Though diabetes and other immunosuppressed condition are at risk of acquiring Mucormycosis, In the present study 2 cases were not diabetic and didn’t had any immunosuppressive condition nor they were treated with steroids for covid-19 treatment. Hence we suggest that mucormycosis could be suspected in immunocompetent individuals also.

Abstract : Atrial fibrillation is the commonest type of arrhythmias with significant mortality and morbidities. There is a correlation between AF and renal impairment and this correlation is complex and may be a manifestation of cardiorenal syndrome, a bidirectional complication of these diseases or its treatment or both coexist in same disease. To evaluate frequency of renal indices abnormality among patients with atrial fibrillation. By using cross sectional descriptive study, randomly selected 52 atrial fibrillation patients admitted to Coronary care unit in Al-Nasiriya city underwent a complete evaluation for renal indices including blood urea, serum creatinine, urinalysis, serum electrolytes, Albumin creatinine ratio and ultrasound for renal system. Also performed questionnaire were obtained from all patients. Patients labeled as chronic kidney disease or underwent to renal replacement therapy were excluded. Mean age of patient’s 59.6±13.1 years and for Age at diagnosis 56.9±14.9. All patients have one or more abnormal renal indices. Most abnormalities appear in urinalysis (100% of patients) followed by abnormal Albumin creatinine ratio (48% of patients), Blood urea in 26.92%, Serum creatinine in 9.6% and ultrasound in 7.69%. 75% had chronic diseases plus AF. Significant correlation between male gender and highly abnormal blood urea (P.value=0.05), serum creatinine (P.value=0.014) and Albumin creatinine ratio (P.value=0.013). Also between direct cardioversion shock and blood urea (P.value=0.018), serum creatinine (P.value=0.006) and Albumin creatinine ratio (P.value=0.047). Blood urea correlated with abnormal echo finding (P.value=0.02) and number of medications that used for atrial fibrillation management (P.value=0.031). Some renal indices is abnormal in Atrial fibrillation patients especially urinalysis, blood urea, serum creatinine and Albumin creatinine ratio. In addition, this abnormality related to gender, using of direct cardioversion shock, echo abnormalities and number of medications for atrial fibrillation.

Abstract : For Patients with coronary artery disease (CAD) accompanied by decreased left ventricular ejection fraction (LVEF), coronary artery bypass grafting (CABG) was the preferred management and superior to pharmacological therapy alone. Health assessment related to the quality of life in patients with CAD and post-CABG is important and intended for evaluating the acquisition of the therapeutic target. Based on the guidelines, treatments of CAD should be accompanied by lifestyle modification and cardiac rehabilitation. The aim of the study was to assess functional capacity changes (∆METs) after phase II cardiac rehabilitation as a predictor of quality of life 3 months after CABG. A cohort study methods on patients with LV systolic dysfunction who underwent CABG between January 2019 and January 2021. Patients were submitted to phase II cardiac rehabilitation, where ∆METs showed changes in functional capacity before and after the program. The abnormality of ∆METs as a predictor was determined by the cut-off point using ROC and AUC curve in the previous study which was 3.25 METs.5 Observe-component was patients’ quality of life 3 months after CABG using Kansas City Cardiomyopathy Questionnaire (KCCQ). The study showed there was a significant relation between ∆METs and KCCQ scores with moderate strength (p<0.01; r = 0.592), and showed the lower ∆METs group had a 5.3 times greater risk of poor quality of life than the higher ∆METs group 3 months after CABG (p<0.01; OR = 5.3). The conclusion of the study showed that Functional capacity changes after phase II cardiac rehabilitation could predict the quality of life after CABG in patients with LV systolic dysfunction by using KCCQ.

Abstract : Brucellosis is a frequent infectious zoonosis over the world, intimidating both veterinary and human public health. The misuse and overuse of antibiotics in Iraq in the veterinary field is associated with the high rate of antibiotic resistance that observed in some zoonotic bacteria directing to cause serious infections in human. The point of this study; is to determine the occurrence of extended-spectrum beta-lactamases (ESBLs) -producing Brucella abortus in the blood of cattle. One hundred blood samples were obtained from cattle in a number of slaughterhouses in different areas of Baghdad. Equal to 10 ml of blood samples were collected from the tail vein of the animals. Blood was divided into two parts; the first part (7ml) in Trypticase soy broth, incubated at 37 °C with 5–10% CO2 for 2-3 days. Later, Bacterial DNA was extracted and a specific set of primers were used for the detection of β-lactamases genes in Brucella abortus isolated using multiplex-PCR technique. of 100 blood samples used in this study 26 isolates (26%) were confirmed to be Brucella abortus species by VITEK-2 System. The ESBLs genes; blaTEM gene was detected in 9 of 26 (34.6%) isolates, followed by blaCTX-M gene in 7(26.9%) isolates, blaAMPC gene in 6 (23.0%) isolates, and blaSHV gene in 4 (15.3%) isolates. This study indicated the high rate of ESBLs- producer Brucella abortus among cattle. Thus, indicating the potential of animals as a source of the ESBLs-producer bacteria that transmitted to human via the food chain or other recreational activities.