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Abstract : Electroconvulsive therapy (ECT) is one of the oldest and most effective methods to treat many psychiatric disorders. Succinylcholine is a short-acting depolarizing skeletal muscle relaxant used to relax muscles and facilitate patient control during intubation, mechanical ventilation, and surgical procedures. The aim of this study was to compare the probable complications and hemodynamic changes created as a result of applying 0.3 and 0.6 doses of Succinylcholine in candidates of ECT. In this clinical trial at Isfahan university hospital, 40 ECT candidate patients were randomly divided into two groups of 20 patients receiving 0.3 and 0.6 Milligrams per Kilogram dose of Succinylcholine. The age, sex, height, weight, and body mass index (BMI) of patients were recorded. Before induction of anesthesia (baseline) and 1, 5, 10, and 20 minutes later, symptoms like systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR) and oxygen saturation (SPO2) measured and compared between two groups. There were no significant differences between the two groups regarding primary data and symptom values (P> 0.05). In patients that received 0.6 mg/kg of Succinylcholine, the prevalence of hypoxia and duration of apnea were significantly higher and the seizure duration was considerably shorter. Administration of Succinylcholine with 0.3 mg/kg lead to fewer complications including frequency and duration of apnea.

Abstract : Citrus medica commonly known as citron is widely distributed in the himalayan regions of India. It contains various phytoconstituents like limonene, hesperetin, Vitamin C, phenolics, flavonones, iso-limonene, pectin, linalool, decanal, and nonanal etc. It is frequently used in traditional systems of medicine for the treatment of cardiac, thyroid, and oestrogen disorders. These activities are due to presence of phenolic and flavanoids content in it. It is also act as mutagenic and exhibits good antioxidant properties. The plant leaves, peels, fruits and their seeds have several pharmacological effects such as antioxidant (reduces reactive oxygen species and malondialdehyde), analgesic and anti-inflammatory activities (inhibitis DPPH and hydrogen peroxide radical scavenging), antilipidaemic (by inhibiting HMG-CoA reductase) and estrogenic activity (increase vaginal epithelial cell cornification and uterine weight) etc. The purpose of this review is to highlight the source, geographical indication, phytochemistry, traditional uses, pharmacological effects and numerous nutraceuticals application of Citrus medica and its main constituent Vitamin C.

Abstract : The effect of positive thinking on the level of depression in diabetic Mellitus patients. Diabetes mellitus is a chronic disease that cannot be cured. It is not contagious but has a high risk of disrupting one's life. This study aims to prove the effect of positive thinking on the level of depression in patients with diabetes mellitus. This type of research is a pre-experimental One-Group Pre-test-posttest Design. The sampling technique is purposive sampling. The number of samples in this study was 34 people. Data collection techniques used Beck Depression Inventory-II (BDI-II). The results of the investigation before treatment were positive thinking depression level in study subjects, mild depression in 12 people (35.3%), depression was 18 (52.29%), and significant depression for 4 people (11.8%). After being given a favorable thinking treatment, the depression level of the study subjects was: normal/not depressed in 1 person (2.9%), mild depression in 17 people (50%), moderate depression in 15 people (44.1%), and significant depression 1 person (2.9%). Paired t-test results: mean before treatment 21.9412, after treatment 19.1765, t = 5.787, and p = 0.000. There is a significant effect of positive thinking on the level of depression in patients with diabetes mellitus. Positive thinking can reduce depression levels in patients with diabetes mellitus.

Abstract : One of key sector to combat covid-19 is healthcare, whose worker are put in high risk affected physical, mental and social. Healthcare worker (HCW) defined as all staff involved to provide treatment for covid-19 patients and are put in higher risk to SARS-CoV-2 exposure than general population. In addition, infected HCW are required to work immediately as the amount of HCW is limited. Indonesia applied entry and exit test in five days to shorten isolation and quarantine period. The policy has also been applied to HCW in Sulianti Saroso Infectious Disease Hospital since January 2022. This study accounted 229 covid-19 confirmed healthcare worker in Sulianti Saroso Infectious Disease Hospital with admission date January 1st – February 28th, 2022. Conversion time was divided into two categories, less than equal to 10 days and more than 10 days. Our study showed out of all, only 20,5% of our healthcare workers had conversion ≤10 days. It means most of the result of exit test RT-PCR on day 5 after confirmed date was positive. We found correlation between symptoms and conversion time (p = 0,0001). We also found significant correlation between severity and conversion time (p = 0,0001) as in line to preceding studies. this study aimed to give recommendation and evaluation on exit test on day 5 for healthcare worker policy.

Abstract : This research aimed to identify and detect each existing failure mode based on probability and severity and provide solutions using the Failure Mode and Effect Analysis (FMEA) method. A company known as PT. Gapura Angkasa in Sultan Hasanuddin Airport was used, which has hundreds of workers in the Ground Support Equipment (GSE) Division, and its operation is fraught with danger and risk. This research identified the cause of the GSE damage, ensuring the safety of workers and the smooth operation of the aircraft and passengers. A qualitative approach was used to examine the condition of the equipment, with the researcher serving as the primary instrument. To obtain information about the failure modes of the GSE at PT. Gapura Angkasa Makassar, the FMEA method was used. This was carried out by determining the risk rating, which is represented by the Risk Priority Number (RPN). The results showed that there were two types of GSE damage, namely BTT and BCL. The engine indicator component in the BTT and the steering column in the BCL had the highest damage, with RPN of 240 and 160, respectively. Routine maintenance is recommended on components with a high probability value to improve their reliability, while special attention should be paid to components with a high RPN level.