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Abstract : The coronavirus disease-19 (COVID-19) pandemic is a problem that is being faced by every country around the world. This study aimed to determine the relationship between the cycle threshold (Ct) value and the levels of Interleukin-6 (IL-6), Interleukin-10 (IL-10) in COVID-19 children without symptoms. This research is an observational study with a cross-sectional study design to analyze the relationship between ACE-2, IL-6, and IL-10 levels in COVID-19 children without symptoms. Ct values were measured by RT-PCR, and levels of Il-6 and IL-10 were measured by ELISA examination. The result showed that low Ct values (<27) were found in 14.3% of patients while high Ct values were found in 85.7% of patients. Correlation test using Spearman Rho's showed no significant relationship that is Ct and IL-6 values (r= 0.058; p=0.742) and Ct and IL-10 values (r= 0.158; p=0.365) with mean IL-6 of 29.65 ± 46.09 (range 2.08-241.58) AndIL-10 average was 11.53 ± 10.17 pg/mL (range 1.13-66.9 pg/mL). The majority of Ct values in asymptomatic child Covid 19 patients were high (85.7%). There is a statistically insignificant relationship between Ct and IL6 valuesAndIL 10 in asymptomatic child Covid 19 patients.