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Abstract : The survival of children with congenital heart disease (CHD) has increased drastically in the last few decades. However, in children with the acyanotic type of CHD, it is often accompanied by symptoms of failure to thrive. This condition is also associated with impaired psychomotor and cognitive development, with negative effects on psychosocial and academic performance and quality of life. This study aims to assess the differences in growth and development of acyanotic CHD children before and after transcatheter closure. This cohort prospective analytic study were conducted on children who had undergone defect closure procedures at H. Adam Malik General Hospital, Medan. Growth and development measurement results were assessed before and after transcatheter closure. The growth assessment using the CDC (Centers for Disease Control and Prevention) and WHO (World Health Organization) growth charts. The development assessment using Denver II. Differences in growth and development before and after transcatheter closure were tested using the Wilcoxon and McNemar method. There were 30 samples have analyzed, the majority aged 1-3 years (46,7%) followed by ages 1 years (30%). Patent ductus arteriosus is the most common acyanotic disease with closure defect (56,7%). There was significant differences in weight, height and nutritional status in children with congenital heart disease between before and after transcatheter procedure (p < 0.05), but there was no difference in developmental status between before and after defect closure (p = 1,000). There is a significant difference between weight, height and nutritional status in children suffering from congenital heart disease before and after transcatheter procedure. But there is no difference in the development of children with congenital heart disease between before and after the transcatheter procedure.