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Abstract : Data from several countries reported a high prevalence of both H. pylori infection and anemia in children. Several studies tried to find the association between H. pylori gastritis and iron deficiency anemia (IDA) in both pediatric and adult populations, but the results remain inconclusive. Knowing that H. pylori gastritis and IDA in children have a long term complication, finding the relationship between the two may be beneficial to eradicate both. This is an observational analytic with cross-sectional design study in children 2 to 18 years old, who were diagnosed with H. pylori and non H. pylori gastritis based on esophagoduodenoscopy (EGD) and Campylobacter-like organism (CLO) tests. A total of 63 children (33 H. pylori and 30 non H. pylori gastritis) with a median age of 12 years (range 2-18 years old) were enrolled between August until December 2021. Blood specimens were then taken for complete blood count and iron profile examination. There were 26 samples (41.3%) who were anemic (11 children with H. pylori gastritis and 15 children with non H. pylori gastritis). There were only 5 (7.9%) children with IDA (1 child with H. pylori and 4 children with non H. pylori gastritis). Based on statistical analysis, there was no significant difference in IDA incidence in children with H. pylori and non H. pylori gastritis (p=0.183). It is concluded that H. pylori gastritis is not associated with iron deficiency anemia in children.