Abstract : Pulmonary embolism (PE) is a serious cardiovascular condition associated with high morbidity and mortality. Despite established risk factors, including obesity, smoking, sedentary lifestyle, and chronic illnesses, public awareness of PE remains limited, particularly in Saudi Arabia. Assessing knowledge, risk factors, and awareness is critical for guiding preventive interventions and educational strategies. A descriptive, cross-sectional survey was conducted among 548 participants from various regions of Saudi Arabia. Data were collected using a structured, self-administered questionnaire covering sociodemographic characteristics, health conditions, respiratory symptoms, lifestyle factors, and PE awareness. Descriptive statistics were used to summarize categorical and continuous variables, and chi-square analysis assessed associations between knowledge and participant characteristics. The majority of participants were aged 21–40 years (73.8%) and female (74.5%), with most holding university-level or higher education (70.3%). Reported health conditions included hypertension (2.0%), heart disorders (4.9%), obesity (11.9%), asthma (7.8%), and smoking (5.7%). Prolonged immobility was reported by 47.6%, and 20.6% reported exposure to environmental pollutants. Respiratory symptoms were noted, with 36.9% experiencing shortness of breath at least occasionally during physical activity, and 43.1% reporting concern about breathing difficulties. Only 34.1% of participants had prior knowledge of PE, with the internet and social media being the most common sources of information (34.1%), followed by courses or lectures (10.4%). Awareness of risk factors was variable; age (82.8%) and treatment availability (78.6%) were most recognized, while knowledge of prevention strategies (33.2%) and lung function testing (14.2%) was limited. Chi-square analysis revealed that age, educational level, and family history of PE were significant determinants of PE knowledge (p < 0.05). Overall, 82.3% of participants demonstrated inadequate knowledge of PE. Public awareness of pulmonary embolism in Saudi Arabia is limited, despite the presence of identifiable risk factors in the population. Digital platforms are the main source of information, highlighting the potential for targeted online educational interventions. Strategies focusing on increasing awareness, promoting lifestyle modifications, and integrating PE education into public health programs are urgently needed to reduce morbidity and mortality associated with this condition.