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Abstract : COVID-19 drastically affected routine healthcare services worldwide. Patients with chronic diseases were at higher risk of missed care due to the pandemic. We aimed to assess burden of missed appointments of routine care among chronic disease patients in Qassim Saudi Arabia. A facility-based cross-sectional study was conducted among patients with chronic diseases visiting randomly selected primary healthcare centers in Buraidah, Saudi Arabia. Data was collected using a structured questionnaire in Arabic which collected information regarding the socio-demographic and care-seeking during the pandemic. Data were analyzed using Statistical Package for Social Sciences version 21.0. A total of 347 participants were included in the study with a mean age of 58 (±11.4) years. About a quarter, 29.7% reported experiencing COVID-19 symptoms. About 38% had Diabetes Mellitus, 23.6% had hypertension (HTN) and 37.8% had both. The proportion of patients who missed an appointment in the last six months preceding the survey was 44.7%. Common reasons for missing the appointment were; the facility was working but they were not able to get the usual care fear of getting COVID-19 infection, and because of the lockdown. A large proportion of patients with diabetes mellitus and hypertension had their appointment missed during the COVID-19 pandemic. The common reasons were related to the pandemic and its response. This calls for healthcare leaders and managers to plan emergency responses such as for pandemics in such a way as to avoid interruption of care for patients with the need for continued care.