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Abstract : Postoperative wound healing has an important role in the success of dental implant surgery. Patients with Diabetes Mellitus may suffer from problems with wound healing following dental implantation. Hyaluronic acid has a multifunctional role in the wound healing process. This study aims to investigate the role of hyaluronic acid in wound healing process and postoperative pain following dental implant surgery in well-controlled type 2 diabetes mellitus patients. The study included 22 dental implants placed in 16 patients with well-controlled type 2 diabetes aged between 45 and 69 years. 0.2% hyaluronic acid (Gengigel, Ricefarma srl, Milan, Italy) was applied three times daily for a week on the sutures in the experimental group, while in the control group, nothing was applied. Postoperative healing was assessed using an Early Healing Index (EHI) after the first week and a healing index (HI) after the second week. Postoperative pain was evaluated with a Visual Analogue Scale (VAS) daily for 1 week. There were no statistically significant differences between the control and experimental groups regarding the healing indexes EHI and HI. There were significant differences in pain intensity according to VAS score on the first and second day after the procedure (P= 0.048, P=0.042 respectively). The results of this study showed that the application of Hyaluronic acid after implant surgery in patients with well controlled diabetes had no significant effect on improving the wound healing process, but may reduce postoperative pain, especially on the first two days after the procedure.