Abstract : The new types of sealer pastes such as Bioceramic increased the difficulty of retreatment and complete removal of root canal filling materials, Therefore, this study aimed to evaluate the effectiveness of XP-3D R files in removing two types of sealer pastes (Bioceramic Hi-flow and Bioceramic sealer). The study sample consisted of 30 single-rooted and single-canal mandibular premolars, the root canals were prepared to F2 size and divided into two equal groups: Group 1 (n=15): the root canals were filled using BC Hi-Flow with warm vertical compaction technique, and Group 2 (n=15): the root canals were filled using BC with single-cone obturation technique, then retreatment was done using PTUR files, then the teeth were extracted longitudinally, and photographed. The mages were analyzed using the AutoCAD program, as the canal space and the amount of residue in each of the two parts were calculated. The XP-3D R files system was not able to completely remove the root canal filling materials in both groups, and the results showed that the amount of root canal filling residues in the BC Hi-Flow group was (14.27%), while in the BC group was (10.86%). There was no statistically significant difference in the percentage of root canal filling residues in the coronal and apical thirds, in contrast to the middle third as the root canal filling residues were (18.20%) in the BC Hi-Flow group, while it was (11.91%) in the BC group. The XP-3D R files showed the ability to reduce the amount of the root canal filling residues more in the BC group and were not able to completely remove the root canal filling residues in any of the samples. The amount of the root canal filling residues in the BC Hi-Flow group was greater in the middle third and the greatest root canal filling residues removal efficacy of these files was in the apical third.