Abstract :
Dorsal wrist ganglion is the most common soft tissue mass of the wrist and hand, originating from the joint capsule or tendon sheath. While surgical excision is considered the gold standard due to its definitive nature, aspiration combined with corticosteroid injection is an attractive, minimally invasive alternative. However, the efficacy of these treatments, particularly in terms of recurrence, remains debated. This meta-analysis was conducted in accordance with the PRISMA guidelines and included seven studies involving 434 patients published between 2019 and 2024. A systematic search was performed using Google Scholar, MEDLINE, and Cochrane databases. Studies were assessed for quality using the Cochrane Risk of Bias tool for RCTs and the Newcastle-Ottawa Scale for cohort studies. The primary outcome was the recurrence rate, analyzed with a random-effects model and heterogeneity evaluated by the I² statistic. The results indicated that aspiration with corticosteroid injection was associated with a higher recurrence rate compared to surgical excision, with an odds ratio of 3.63 (95% CI 1.25 to 10.54, p = 0.02). Moderate heterogeneity (I² = 69%) was noted, potentially due to variations in corticosteroid types, patient characteristics, and follow-up periods. Surgical excision offers a long-term solution with lower recurrence rates but involves a higher procedural burden. Aspiration with corticosteroid injection, while minimally invasive and quicker, carries a higher risk of recurrence, making it more suitable for patients prioritizing less invasive treatment or with contraindications to surgery. This analysis highlights the need for individualized treatment based on patient preferences, clinical presentation, and resource availability.