The visceral adiposity index (VAI), which is linked to the risk of insulin resistance (IR), cerebrovascular illness, and metabolic syndrome, assesses the amount of damage to visceral adipose tissue. One of the most extensively used methods for determining IR is homeostatic insulin resistance (HOMA-IR). The goal of this study was to determine whether or not the VAI score correlates with HOMA-IR in a group of young adults without diabetes. This is a cross-sectional research was done at Hasanuddin University Makassar from January to March 2021,. Anthropometric measurements were taken. Each person had testing for their lipid profiles, fasting blood glucose, and fasting insulin. Values for the VAI and HOMA-IR were calculated. As statistical tests, the Person Correlation Test, and Chi-square were utilized. As the results, 31.10±3.01 years was the average age. The Receiver Operating Characteristic (ROC) curve study revealed that the VAI cut-off value for HOMA-IR prediction in males was 2.37, while that in females was 2.25. VAI has a positive relationship with HOMA-IR in both men and women (p<0.001). The male group with a VAI value of greater than 2.37 had a 41.6 times greater potential of having an IR compared to the male group with a VAI value of less than 2.37. Female with a VAI value greater than 2.25 are 24.9 times more likely to have an IR than female with a VAI value less than 2.25. In conclusion, VAI has a significant correlation with HOMA-IR in the non-diabetic young adult population.