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Abstract : Myasthenia Gravis (MG) is a neuromuscular disease in which autoantibodies against the acetylcholine receptor (AChR) cause muscle weakness. AChR antibodies are very specific in MG because they are found in about 85% of cases. There are two MG subtypes based on age of onset, namely MG Early Onset (<50 years old), dominated by women, and MG Late Onset (≥50 years old), dominated by men. Several studies have shown different results regarding AChR antibody levels in both ages of onset and gender. The present study is observational analytic research that used a cross-sectional design. The subjects were 33 MG patients selected based on inclusion and exclusion criteria using consecutive sampling. The research data used from secondary data. The researcher used the Spearman and Eta Test to analyze the data. The majority of MG patients were dominated by women (72,7%) and had age of onset <50 years old (67%). The median of AChR antibody level in MG patients was 30.7 pmol/L. The results of the correlation statistical test between the age of onset and AChR antibody levels showed p=0.808 and r=0.044. The correlation test between gender on AChR antibody levels showed p=0.759 and r=0.056. There is no significant correlation between age of onset and gender with acetylcholine receptor antibody levels.