Abstract : Primary malignant lesions in seminal vesicles are rarely observed in clinical practice. Seminal vesicle mainly observed with secondary tumours, and the prostate is the most common source, which is frequently caused by disseminated disease or contiguous spread from an adjacent organ. The main presentation is hematospermia and cancer diagnosed with a CT or MRI scan, followed by surgical resection of this tumour. This literature review concentrates on this rare cancer due to the scarcity of data regarding management techniques and the fact that the treatment is frequently customised to the individual. We summarise and analyse the data from the case reports of the main types of cancer observed in seminal vesicles.