Support Email Address
support@azerbaijanmedicaljournal.net

About the Journal

Download [This article belongs to Volume - 62, Issue - 09]

Abstract : The purpose of this study was to assess the common clinical presentations of fixed ‎drug eruption (FDE) among Iraqi patients.‎ This is a multicenter cross-sectional descriptive study. One hundred and sixty patients who had FDE were seen in the Departments of Dermatology and Venereology at Al-‎Saddir Teaching Hospital and Ibn-Sena Teaching Hospital, Iraq, during the period from Oct. 2017 to Oct. 2018. A full history and clinical examinations were done for every patient. An oral provocation test was done for some patients. A skin biopsy was done for some patients to confirm the diagnosis. The age of the patients was 37.2 ± 16 years. The male-to-female ratio was 1.2:1.‎ Most of our patients presented during the first week of rash appearance as they ‎constituted 77.5% of patients. The shortest time of presentation after taking the causative medications was 30 ‎minutes, whereas the longest duration from taking the insult medication was within ‎two weeks. ‎ Multiple lesions were encountered in 76% of the patients and the upper extremities ‎were the most frequently affected area in 26% of the patients. The most common morphological presentation in a patient with FDE was patches ‎‎49% and erosive type 17%. Itching was the most ‎common symptom suffered by 42% of patients. The most common culprit agent of FDE was co-trimoxazole 47.5%. FDE is a common cutaneous disorder seen in dermatological outpatient clinics. Recurrent multiple patchy and erosive lesions are ‎the commonest clinical presentation. The upper extremities are the most anatomical sites affected by FDE. Pruritus is the most commonest associated symptom.‎