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Abstract : The study aims to know the effect of HP urinary tract inhibitors on the accumulation of calcium oxalate crystals formed, to clarify the mechanism of the formation of urinary tract stones where (98) pregnant women aged between (19 to 42) years with small stones were diagnosed and suffering from abdominal colic, were collected and then underwent treatment for a month. They took three types of therapies that break up the stones. Calcium levels were measured before the treatment and after 30 days. The results were calculated statistically and scientifically evaluated.