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Abstract : Children are known to be less infected by Coronavirus disease 2019 (COVID-19) rather than adults. However, they are still a vulnerable group and the incidence of patient’s admission to the hospital continues to increase. Therefore, the aim of this study was to describe the clinical characteristics and outcome in children infected with SARS-CoV-2 who were treated at the three participating referral hospitals for COVID-19 in North Sumatera. This was a cross-sectional descriptive study conducted at a referral centers for COVID-19 in North Sumatera, Indonesia. The data on clinical characteristics and outcome of children (aged ≤ 18 year-old) with COVID-19 illness and who tested positive for SARS-CoV-2 by RT-PCR from April 2020 - March 2021 were reviewed and analyzed. A total of 218 children were hospitalized and confirmed COVID-19 positive with the majority were more than 10 year-old (44.5%), girl (54,5%), and the common symptoms were fever (75.6%), cough (67.8%) and coryza (41.3%). Even among the symptomatic COVID-19 cases, severe manifestations are seen in very few children. Most of the patients had mild to moderate disease, and only 5,9% had a severe or critical illness. The mortality rate of children with SARS-CoV-2 was 6,3% (7/218). In the early pandemic, the majority of children were found to have mild to moderate symptoms with good outcomes. Severe and critical illness were observed in children were associated with underlying conditions.