Schistosomiasis is a neglected tropical disease that is transmitted by freshwater and snails, The intermediate snail that transmits schistosomiasis in Indonesia is O.h. lindoensis. The snail is amphibian. The survival of the O.h. lindoensis snail is supported by the appropriate climate and environmental habitat. Climate change towards schistosomiasis infection has important implications for the production, survival and fertility of schistosomiasis snails. This paper aims to describe the condition of the physical environment and the infection rate of Sistosoma japonicum cercariae in schistosomiasis intermediate snails in Dodolo Village, Poso Regency. The survey results from 25 habitats showed that the water temperature was between 200C-300C, 84% pH of the water was at a neutral acidity level (7), the soil pH of the snail habitat varied from 4.0 - 7, and 60% of the habitat type was found in the cacao plantation waterways. inhabitant. Cercarial infection rates range from 0-50%. Physical environmental factors such as water temperature, water pH, soil pH and habitat type support the breeding of the O.h. lindoensis snail. The level of cercarial infection in O.h. lindoensis snails differed between each habitat.