About the Journal

Download [This article belongs to Volume - 63, Issue - 09]

Abstract : In the current study, a Pt(II) complex including quercetin, naringinin, and apigenin was created and structurally characterized using spectrum techniques. For their potential to fight breast cancer and microbes, the Pt(II) complexes were studied. The complex significantly affected Staphylococcus aureus, Escherichia coli, Candida alblicans, and Aspergillus niger, according to the results of the study on its antibacterial activity. Using the MTT assay, it was examined whether the Pt(II) complex was cytotoxic to the human breast cancer cell line MCF7. In comparison to the reference medicine 5-fluorouracil (5-FU), cytotoxicity studies indicated that the Pt(II) complex demonstrated moderate cytotoxicity against the development of these cancer cell lines. These novel complexes may be exploited for these therapeutic purposes, according to this study's findings.