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Abstract : Antimicrobial resistance (AMR) is a major threat to public health imposing significant health and economic burdens on healthcare system and patients. Routine clinical microbiology laboratory data provide a profile of the susceptibilities of specific bacteria to antimicrobial agents for monitoring and responding to emerging antimicrobial issues. Data can be utilized to help in the selection of empirical therapy by selecting the most appropriate antibiotics and also for environmental (HAI) surveillance. Although Antimicrobial stewardship programs focus on antibiotic prescribing practice, it is supported by an understanding of local antibiotic susceptibility trends, which in turn depends on the availability of a reliable medical microbiology laboratory resource.