Abstract : Diabetes mellitus define as a collection of metabolic disorders recognized by elevated blood glucose levels over a long period. It's happens throughout the world, but commonly (diabetic from second type) in countries which are considered more developed. The greatest enhance in prevalence is happening in countries which are classified as middle and low income such as Asia and Africa. To assess effect of cinnamon on patients with diabetes mellitus in addition to it's complications and make a comparison between various patients responses who administering metformin in Babylon Governorate. The present study is a randomize prospected, clinical study. This study is carried out in Merjan Medical City, Medicinal Ward, and Malls. This work started at September 2021 at Babylon Governorate. There is reasonable indicator related to the wide spread of good devices for assessment of glucose level in blood. Regarding to the their keeping and standardization locally at regular time and clinical / biomedical engineering departments can almost give additional advice. Sample consist of 30 cases in Babylon Governorate was selected randomly. All the cases present in Merjan Medical City, Markets and Malls. Patient who taking metformin and cinnamon further reduction in blood glucose level more than patients who taking only metformin. According to the results showed that the using of cinnamon with metformin will contribute in the lowering of blood glucose level to a range best than range that can been get when using metformin.